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All of this is to say, patients and physicians are being driven to GLP-1s, particularly semaglutide, for managing obesity
Pendulum GLP-1 Probiotic doesn't appear to have been studied in any clinical trials, and we haven't come across any evidence proving that this proprietary formulation increases GLP-1 levels

I see many patients who say, Ill just wait for the new triple drug. As a doctor, I strongly advise against this strategy for three reasons: Obesity is a progressive disease

That fear turned out to be badly overblown
in contrast, the 4 mg dose of efpeglenatide had no statistically significant effect on HF hospitalisation