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Description
Simtuzumab (SIM) SIM is a monoclonal antibody against the enzyme lysyl oxidase-like 2 (LOXL-2) responsible for the cross-linking of collagen and overexpressed during the fibrosis progression [80]
While frank hyperglycemia is uncommon, those with underlying insulin resistance or diabetes should be monitored for any change in glucose control
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Baltimore functional medicine specialist, Eric Nager, M.D

Heres what to expect, explained clearly and honestly
