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The clinically most relevant and important action of DPP-4 inhibitors is the endogenous elevation of the incretin hormone concentration of GLP-1 that consecutively leads to a glucose-dependent stimulation of insulin secretion and an inhibition of glucagon secretion (10)
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doi: 10.1038/ncomms14063
The type 1 diabetes research and advocacy organization JDRF and other diabetes nonprofits could help advance the science by funding academic research studies
