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doi: 10.3945/ajcn.112.047563

Both represent transformative advances in metabolic health
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Injectable semaglutide delivers nearly 100% of the active compound directly into subcutaneous tissue, where it enters the bloodstream efficiently

Dehydration is a related concern, as both reduced fluid intake (due to appetite suppression) and increased fluid losses (from gastrointestinal side effects) can contribute to volume depletion
