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No, degradation is gradual

Common side effects include: Nausea and vomiting Diarrhoea or constipation Reduced appetite Abdominal discomfort or bloating Injection site reactions (redness, itching, or mild swelling) These effects can often be managed by eating smaller, lower-fat meals, avoiding lying down immediately after eating, staying well hydrated, and adhering to the gradual dose-escalation schedule

During significant caloric restriction, ensuring adequate dietary protein (at minimum 1.2 to 1.6 grams per kilogram of body weight) supports muscle preservation and complements the favorable body composition changes these medications produce

Proton-pump inhibitors: Understanding the complications and risks