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This action may counteract any appetitelowering activity caused by the high GLP1 levels, leading to an insignificant impact on body weight

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It all plays a role in weight gain. The Centers for Disease Control and Prevention estimates that in 2024, more than 25% of people with diabetes used a GLP-1

Given existing evidence, triple combination therapy can be expected to provide additional cardiorenal protection, although further randomized controlled trials are needed to determine whether triple combination therapy actually has additive or synergetic effects compared with mono or dual therapy

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