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BENEFITS OF SWITCHING FROM ONE GLP1RA TO ANOTHER 3.1
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2 Additionally, GLP-1 receptor agonists have the added benefit of weight loss
Thus, several studies have demonstrated the presence of prohormone convertase 1/3 [PC1/3, the processing enzyme that cleaves proglucagon to generate GLP-1 (105)] and fully processed GLP-1 in rodent and human -cells and islets in culture (106110), and GLP-1 can be detected in the media, suggesting that it is secreted from the -cells
