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Using a projected Target Scan algorithm, miR-27a may target the PPAR gene

The GCGR component is particularly important for researchers studying energy expenditure rather than just appetite suppression

Butler J, Packer M, Siddiqi TJ, Bohm M, Brueckmann M, Januzzi JL, et al

The human GLP-1R was modified with its native signal sequence (M1-P23) replaced by the HA signal peptide to facilitate receptor expression
