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Treating these conditions costs a lot of money, and its clear that weight loss can significantly reduce these risks

However, LDL levels and SBP did not made significant different (Supplemental Table 12)

This effect is not unique to retatrutide
Pharmacological guidance recommends discontinuing therapy after at least 5 half-lives to minimize fetal exposure

In addition, the different distribution of SGLT2 and GLP-1R may be involved
