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The study in Molecular Nutrition and Food Research demonstrated that nicotinamide supplementation in mice on a high-fat diet reduced body weight gain, increased energy expenditure, and upregulated genes involved in thermogenesis and fat oxidation, including PPARalpha and PGC1alpha
If this is the case, your healthcare provider may wait another month before increasing your dose
10.1172/JCI116186
Hunter Gibble T, et al
One mild-to-moderate flare was observed at 8 months
