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Abbreviations A: Amyloid AD: Alzheimers disease BBB: Bloodbrain barrier CSF: Cerebrospinal fluid CV: Cardiovascular FDA: US Food and Drug Administration GLP-1: Glucagon-like peptide-1 GLP-1RA: Glucagon-like peptide-1 receptor agonist hs-CRP: High-sensitivity C-reactive protein MACE: Major adverse cardiovascular event MCI: Mild cognitive impairment OD: Once daily OW: Once weekly p-tau: Phosphorylated tau s.c.: subcutaneous T2D: Type 2 diabetes References Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chtelat G, Teunissen CE, et al

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doi: 10.1016/j.ceb.2014.09.004 16 GarciaDShawRJ

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Legislation Keep up with state legislation in the areas of pill presses, prescription drug affordability boards, and drug importation

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The GLP-1 Boosting Meal Pattern: Putting It Together Individual foods matter less than meal patterns

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The most recent Phase 3 trial showed discontinuation rates of 12-18% due to adverse events, higher than existing GLP-1 medications

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