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This conversion happens primarily in the liver and requires adequate levels of glutathione and other cofactors

Learning more about how tirzepatide influences metabolism can help explain why your cycle might seem off, adjust, or feel different while on the medication

(In the past, Siegel received research funds from Vivus, which makes Qsymia, a weight-loss medication that is not a GLP-1 agonist.) GLP-1 agonist medications cause the pancreas to release insulin, which helps control blood sugar, and they slow your gastrointestinal tract down, making you feel full longer and reducing hunger, he explains