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Description
They reduce the release of cytokines like IL-1, IL-6, and TNF, upregulate the anti-inflammatory cytokine TGF-, and downregulate the expression of disease-associated microglial (DAM) genes, ultimately enhancing A clearance [74]

Nutr Res Rev, 2018

SREBP-1c: sterol regulatory element-binding protein-1c

Tachyphylaxis, a progressive decrease in the gastric emptying effect over time, has been demonstrated with long-term use of weekly formulations such as semaglutide and tirzepatide [4, 22]
The other half
