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After careful analysis and comparison between the four treatment groups, we found that normal CSMCs are capable of producing several cytokines and chemokines at the basal level, while inducing inflammation by LPS stimulation caused a marked increase in the expression of TNF-, IL-1, M-CSF, TCA-3, and SDF-1

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[DOI] [PubMed] [Google Scholar] 626.Sonne D.P., Engstrom T., Treiman M

In one clinical trial , people who took the highest dose of Saxenda (3 mg) lost around 5-10% of their body weight after about a year on the medication