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Description
The intranasal administration of peptides for treating a disorders originating in the brain is not a novel concept, but only the vasopressin analog desmopressin has been used clinically by this route for several decades to treat diabetes insipidus (Kastin and Pan, 2006)
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MacIsaac RJ, Ekinci EI, Jerums G
Cofactor-Dependent Enzymatic Throughput Metabolic flux is ultimately executed through enzyme systems whose catalytic activity depends on micronutrient cofactors
In fasted rats, co-administration of GLP-1 and GLP-2 leads to a greater inhibition of small bowel motility relative to either monotherapy [793]
