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In addition, because the tissues in which the GLP-1 receptor is expressed are not limited to the gastrointestinal and pancreatic glands, GLP-1RA can reduce cardiovascular risk in addition to lowering glucose and reducing body weight
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Based on typical drug development timelines and the promising retatrutide results from earlier phases, potential approval could come in late 2026 or 2027, though regulatory timelines can vary

89% of adults taking Wegovy HD lost 5% or more of their body weight in a separate clinical study
