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Because this was an observational study in a specific clinical population, randomized clinical trials are needed before GLP-1 medications can be recommended for treating addiction. The team believes the findings could help guide future approaches to addressing substance use-related health issues by identifying biological pathways that may be targeted therapeutically

FIGURE 3 Time-to-onset analysis The onset time and WSP (weighted signal proportion) analysis results for the clinical priority signals of adverse events (AE) in subcutaneous injection and oral administration are presented in Table 3

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Zepbound should be used with a reduced-calorie diet and increased physical activity

This was thought to be due to gastroparesis secondary to GLP-1 agonist use which leads to stomach paralysis