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Description

Several mechanisms have been proposed to explain these newfound cardioprotective effects of GLP-1RAs

A Narrative Review for Clinical Practice

Cochrane, 2023

These medications also show cardiovascular and renal benefits, such as reducing blood pressure, improving endothelial function, and lowering the risk of cardiovascular events like myocardial infarction and stroke [6][16]

As is often the case, a failure in science, in reality, did not invalidate a strong GLP-1 hypothesis, rather it improves, or refines, it for follow up investigations