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Staying well-hydrated can also alleviate gastrointestinal symptoms
At higher effective drug exposure, these musculoskeletal symptoms could become more frequent or more intense, further reducing quality of life and exercise tolerance

routine ultrasound screening is not standard UK practice Risk-benefit discussion : Shared decision-making addressing potential adverse effects, including pancreatitis risk, balanced against substantial metabolic benefits Ongoing monitoring recommendations: Regular clinical review : Initially at 48 week intervals during dose titration, then 36 monthly once stable Symptom surveillance : Systematic enquiry about abdominal pain, nausea, vomiting, or other concerning symptoms at each consultation Indication-specific monitoring : For diabetes patients, HbA1c every 36 months as per NICE NG28

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Achieving sustainable weight loss requires more than just medication
