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Yes when medically supervised, GLP-1s are considered safe for ongoing use

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Semaglutide may possibly increase the expression of ubiquitin ligase parkin, leading to ubiquitination of mitochondrial proteins, effectively marking them for removal through mitophagy activation [137]

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Obesity in hidradenitis suppurativa: are GLP-1 receptor agonists the new frontier

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Newman NJ, Bruce BB, Biousse V (2025) GLP-1 RAs for idiopathic intracranial hypertensiontime for a trial

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As more details become available for the Administrations agreements, we will see how state Medicaid responds. The Department of Health and Human Services referred questions to the White House, which did not respond to requests for comment on states termination of Medicaid coverage for the weight loss drugs

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