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Though it helps patients save money and lessens the burden of supply shortages, compounded semaglutide has generated ethical and safety issues in the medical field

Evidence linking GLP-1 therapy to cortisol changes remains largely indirect, derived from reductions in inflammation markers and metabolic stress indicators

Patients may benefit from: Referral to specialist weight management services Dietitian consultations for personalised nutrition advice Psychological support for emotional eating or body image concerns Structured physical activity programmes Peer support groups or digital health platforms Long-term treatment planning should address realistic expectations
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