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When you lose a significant amount of body weight by any means, some lean mass reduction is expected

Multiple FDA-reviewed GRAS notices did not reveal evidence of harmful gut effects at intended use levels, although none of the studies directly assessed gut bacteria composition in humans

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In the exam room, Jane and I ultimately decided to try an older medication, metformin, for now to help with weight loss alongside other lifestyle changes

Clinical trial participants reported the most discomfort when they first started taking tirzepatide, or when they increased their dose