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Efficacy and Safety of a Fixed-Ratio Combination of Insulin Degludec and Liraglutide (IDegLira) Compared With its Components Given Alone: Results of a Phase 3, Open-Label, Randomised, 26-Week, Treat-to-Target Trial in Insulin-Naive Patients With Type 2 Diabetes

J Obes Metab Syndr 2023;32:2545.ArticlePubMedPMC 87

Insulin breakthrough In the end the final breakthrough was made by a team at the University of Toronto (figure 6)

Oral bioavailability differs significantly from subcutaneous delivery, which means the degree of prior receptor adaptation is not directly comparable

Given she was then just 30 years old and was one of the youngest scientists in her division this was highly daunting