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For adults over 65, no dose adjustment is required, but careful monitoring for adverse effects is prudent as older adults often have multiple comorbidities and medications that increase complication risk

f you experience severe vomiting, dehydration symptoms (very dark urine, dizziness, dry mouth), or are unable to keep fluids down

By addressing the root causes of weight gain, Brello focuses on building confidence and lasting results

Providers should monitor weight trajectory , GI tolerability (nausea, vomiting, constipation) , signs of pancreatitis (persistent severe abdominal pain vomiting), gallbladder disease (RUQ pain, fever, jaundice), hydration/renal function when clinically indicated (risk of AKI with severe GI effects), blood pressure , and glucose metrics (especially if combined with insulin or sulfonylureas due to hypoglycemia risk)

Verify the compounding pharmacy is licensed and inspected, and request proof of manufacturing standards