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Description
They stimulate glucose-dependent insulin secretion from pancreatic beta cells

Summary of Revisions

Clinical trial data from the STEP program showed that semaglutide 2.4mg weekly produced average weight loss of 14.9% of body weight over 68 weeks, compared to tirzepatide at 15mg which achieved approximately 22.5% in the SURMOUNT trials

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The dual mechanism does not appear to reduce the gastroparesis risk
