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By mimicking the effects of endogenous GLP-1, they stimulate GLP-1 receptors, including those in cardiomyocytes and blood vessels (36)

While semaglutide doesnt seem to affect birth control pills, tirzepatide may reduce absorptionso backup contraception is advised for 4 weeks after starting or increasing the dose

doi: 10.1111/j.1742-7843.2009.00494.x 32 KildemoesHWSorensenHTHallasJ

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Second, we have not considered several practical limitations and costs associated with increasing medication use, such as marketing and advocacy required to reach high rates of use