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glp 1 agonist mechanism of action of GLP-1 agonists – My Endo Consult Consensus Recommendations on GLP-1 RA
Description
The theoretical benefit compared to the peptides is reduced receptor desensitisation and a different tolerability profile, though whether that translates to clinically meaningful differences in nausea, vomiting and discontinuation rates is still under investigation

doi:10.1016/j.clinthera.2011.04.024 123

doi:10.1152/ajpregu.00519.2009 280

Food and Drug Administration (FDA) recently flagged concerns about unapproved products labeled as for research use only but sold directly to consumers, many claiming the same GLP-1-based magic

Maybe GLP-1 drugs seem to do everything because obesity (and high blood sugar) are broadly bad for you, and anything that reduces obesity (or high blood sugar) is broadly good for you
