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Dr Nora Volkow, director of the US National Institute on Drug Abuse, has noted that GLP-1 drugs show promise in reducing cravings not just for food, but for substances like alcohol and nicotine

Eli Lilly's TRIUMPH Phase 3 program includes multiple trials across different populations: TRIUMPH-1: Obesity without type 2 diabetes (NCT05929066) TRIUMPH-4: Obesity with type 2 diabetes Additional trials: MASLD/NASH, cardiovascular outcomes, kidney outcomes What Trial Enrollment Includes Free study medication (retatrutide or placebo

Ensuring adequate protein, iron, zinc, and biotin intake helps minimize hair loss

Use the Journey Card to record photos and notes after each dose change or milestone

A randomized study has shown that starting at a lower dose (0.0675 mg measured as five clicks made by the dose selector dial and titrating slowly improves adherence and reduces adverse events without compromising efficacy (284)