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GLP-1 receptors are expressed in key reward-related brain regions , including: The ventral tegmental area (VTA) and nucleus accumbens , which form the core of the mesolimbic dopamine pathway The prefrontal cortex , involved in executive function and impulse control The amygdala , which processes emotional salience and stress responses The prevailing hypothesis suggests that GLP-1 receptor activation may modulate dopamine signalling in reward circuits

Theyre great for the right person, said Moore, who is also a professor of clinical practice, medicine and internal medicine at the University of Colorado School of Medicine and researches best practices in patient care through the Brown Moore Endowed Chair for Excellence in Patient Experience

Recent research showed patients on GLP-1s having reduced risk of cancer, including nonobesity-related cancers

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