keeping weight off after semaglutide Maintaining Loss Ozempic: Long-Term Success How to Maintain Weight Loss
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doi: 10.1210/endo.139.5.5998 151 ZhuTLiCZhangXYeCTangSZhangWet al

New England Journal of Medicine, 375(19), 1834-1844

From conversations I've had today, it sounds like this is what rankled Makary and caused the tweet last night

Contraindications Do Not Use If You Have a personal or family history of medullary thyroid carcinoma (MTC) Have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Have had a serious hypersensitivity reaction to tirzepatide or any component of the formulation Are pregnant, planning to become pregnant, or breastfeeding Warnings and Precautions Acute pancreatitis: Has been reported in clinical trials
Yes, for average weight loss results, Zepbound demonstrates superior efficacy-approximately 2.8x greater average weight loss than Contrave in clinical trials