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These once-weekly injectable peptide medications are key elements in known FDA-approved brands that treat diabetes, obesity and excess weight

Theres no guidance on changing GLP-1 dosage for weight loss maintenance, but your doctor may be willing to experiment with smaller or less frequent injections

Because of the limitations of this type of study, the research cant prove that hormone therapy directly caused the additional weight loss but it supports the idea that estrogen may influence how some women respond to GLP-1s

In vivo studies

Rapid weight loss alters sex hormone binding globulin levels, which affects free estrogen and progesterone availability