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The very high demand combined with the very high prices and limited insurance coverage for these weight loss drugs drove the rise of the market for compounded GLP-1s, says Mike DiStefano, PhD, an assistant professor at the Center for Pharmaceutical Outcomes Research at the University of Colorado in Anschutz

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Keywords: Pharmacokinetics, semaglutide, curve plasma concentrations, type 2 diabetes, obesity, glucagon-like peptide-1, drugdrug interaction Introduction Type 2 diabetes (T2D) and obesity are major public health burdens with an important economic impact and their incidences have increased in the past decades

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The research team included Ivy Shi, MD, MBA, Robert W