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In contrast, non-ATP-linked oxygen consumption tended to increase in cells exposed to irisin or Ex-4 compared to controls (Figure 5 B)

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GLP-1 Signaling Pathway Glucagon-like peptide-1 (GLP-1) exerts its physiological effects by binding to the GLP-1 receptor (GLP-1R), a class B1 G-protein-coupled receptor (GPCR)