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The SURMOUNT-1 trial [5] showed similar GI rates to semaglutide
In the SURPASS 2 trial, Tirzepatide at all doses (5mg, 10mg and 15mg) was found to result in greater weight loss than semaglutide 1mg
The 10mg group achieved 19.5% reduction
Both play a role in controlling blood sugar and managing weight, so it makes sense to wonder if combining them is safe
