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Conversely, in SAVOR-TIMI 53 (saxagliptin assessment of vascular outcomes recorded in patients with DM thrombolysis in myocardial infarction) trail, Scirica et al
Los efectos adversos gastrointestinales se atribuyen al aumento en la actividad de GLP-1 que estos medicamentos generan, y no existen medidas teraputicas para mejorar dicha sintomatologa42,71-73
[DOI] [PubMed] [Google Scholar] 37.Cudini A., Fierabracci A
Most people think of peptides as working on the stomach
The widespread expression of GLP-1R suggests that GLP-1 plays pleiotropic physiological roles beyond insulin secretion
