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In a 48-week phase II clinical trial conducted on patients with type 2 diabetes and obesity, treatment with a dose of 10 mg/kg of bimagrumab resulted in a significant reduction in fat mass by 20.5% (compared to 0.5% in the placebo group), while lean body mass increased by 3.6% (as opposed to a decrease of 0.8% in the placebo group), leading to an overall body weight reduction of -6.5%, which was substantially better than the -0.8% observed in the placebo group

In August last year, Williams said she was taking a weight-loss medication, Zepbound, after struggling to shed kilograms through dieting and exercise after her two pregnancies

Its very successful, Falardeau said

Although there is not a lot of data to support the use of dual and triple agonists for hard cardiovascular outcomes, the available trials suggest that the use of these therapies improves cardiometabolic risk factors, such as reducing blood pressure, triglycerides, and low-density lipoprotein cholesterol (LDL-C)

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