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Sick-day guidance is especially important for people at risk of dehydration or ketoacidosis

Check with your doctor immediately if any of the following side effects occur: Less common Belching bloated, full feeling excess air or gas in the stomach or intestines gaseous stomach pain heartburn passing gas recurrent fever stomach discomfort, fullness, or pain yellow eyes or skin Rare Burning feeling in the chest or stomach indigestion stomach upset tenderness in the stomach area Incidence not known Anxiety blurred vision chest tightness chills cold sweats confusion cool, pale skin cough darkened urine difficulty swallowing discouragement dizziness fast heartbeat feeling sad or empty headache hives, itching increased heart rate increased hunger irritability lack of appetite large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of consciousness loss of interest or pleasure nausea nightmares pains in stomach, side, or abdomen, possibly radiating to the back puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness of the skin seizures shakiness skin rash slurred speech tiredness trouble breathing trouble concentrating trouble sleeping unusual tiredness or weakness vomiting Some side effects may occur that usually do not need medical attention

Using RWE research to extend clinical trials in diabetes: an example with implications for the future

It's because they're harder to measure and easier to address once the other variables are locked in

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