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Zepbounds label lists suicidal ideation as a side effect

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Pancreatitis Caution (Class-Level) GLP-1 class drugs carry a pancreatitis precaution in FDA prescribing information for approved agents such as tirzepatide and semaglutide, and alcohol is an independent, well-established pancreatitis risk factor

Meanwhile, as the ASMBS notes, bariatric surgery patients can lose up to 60% of excess weight within six months of surgery and 77% of excess weight within 1 year of surgery

MAUD-Obesity Trial (n = 3,276): Alcohol-related hospitalization occurred in 10.2% of newer GLP-1 RA users and 28.5% of MAUD users