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For more information: Luca Busetto, PhD, is a professor in nutrition and dietetic sciences in the department of medicine and director of the Graduate School of Clinical Nutrition at University of Padova in Italy and director of the clinical nutrition unit at Padova University Hospital

doi: 10.1016/0304-3940(91)90305-d

Aging Signs Substantial weight loss can cause lines and wrinkles to become more apparent

The use of glucose-lowering agents that provide significant weight loss, particularly GLP-1 RA with high weight loss efficacy, should be considered as they can often provide 1015% weight loss or more

The medication's long half-life provides some buffer, and many patients do not experience immediate return of appetite or weight gain after a single missed injection