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GLP-1RAs exert broad anti-inflammatory, metabolic and neurotrophic effects [147], but the heterogeneity of Alzheimers, Parkinsons and Huntingtons disease demands personalized strategies

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Among children ages 2 to 19, obesity rates climbed from 18% to 26%, and they rose from 30% to 38% among adults 20 and older

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The researchers say in the paper only that All participants received a dietary intervention intended to produce 10% weight loss in approximately 14 weeks. That suggests, per other Lilly-funded trials, advice to restrict calories by 500 to 700 per day