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Description
The key difference is choice: you're choosing smaller amounts because you feel full sooner, not because bread is forbidden

A subsequent combined analysis of the STEP 14 studies showed that gastrointestinal adverse events (nausea, vomiting, diarrhea, and constipation) were more common with SMG than with placebo but typically mild to moderate and transient, with weight loss being largely independent of gastrointestinal adverse events [103]

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Dedicated long-term trials investigating the benefits of such therapies on hospitalisation, major cardiovascular adverse events and all-cause mortality are required
