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How Boxed Warnings Affect Drug Prescribing Boxed warnings are primarily directed at healthcare professionals, who are responsible for: Informing patients about the risks before prescribing the medication Ensuring proper monitoring to minimize potential adverse effects Weighing the risks vs

In the Phase 2 clinical trial published in The New England Journal of Medicine in 2023, participants taking the highest dose of retatrutide lost an average of 24.2 percent of their body weight over 48 weeks