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Key findings from the new studies: ARTIOS trial: Patients who switched to Kesimpta after experiencing relapses or MRI activity on other oral treatments showed fewer relapses, suppressed MRI activity, and over 90% achieved no evidence of disease activity (NEDA-3)

The intermediate was finally reacted with the appropriate amine-containing drug (+)-MK-801 (2,2-diphenyl-1-amine

Blood pressure control was unaffected in the LEADER trial (N=9,340), where 82% of patients were on renin-angiotensin system inhibitors and no signal of hypertension worsening appeared [19]

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