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Global scientific output trend for BMC Med Inform Decis Mak 2020;20:291

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Reduction in alcohol consumption is a particularly relevant outcome given that GLP-1RAs appear to be most effective for individuals with higher baseline alcohol consumption

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On mechanism and biomarker potency, retatrutide is, on paper, the most powerful insulin-sensitizing candidate in the list, chiefly because it produces the largest reductions in the weight and ectopic fat that drive insulin resistance in most women with PCOS