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In addition to the direct nephroprotective effect, GLP-1R agonists have indirect protective effects as they decrease the incidence of many risk factors associated with kidney injury

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This combination is especially beneficial for women undergoing hormonal changes, as it addresses both metabolic challenges and management concerns

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Exclusion criteria included diagnosis of any form of diabetes or glycated hemoglobin 6.5% at screening, and contraindications to undergoing MRI