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Compared with healthy cartilage, degenerated cartilage shows lower GLP-1 receptor expression ( Analgesic effects Body weight Two studies investigated the effects of GLP-1 RAs on body weight in murine models of osteoarthritis, yet reported contradictory findings

10.1177/2042098616667352 44 JavedH.Kogilathota JagirdharG
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The high proportion of fat reduction within overall weight loss indicates that the risk of muscle loss accompanying weight reduction was minimized

Here, we will discuss in-depth the actions of GLP-1 and its analogues in immunomodulation and related signal pathways in the setting of a number of diseases