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Trial Registration The trials were registered at ClinicalTrials.gov (identifiers: NCT02054897, NCT01930188, NCT01885208, NCT01720446 and NCT02207374)

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Glucagon-like peptide-1 (GLP-1) is a natural hormone released in the intestines to regulate blood sugar levels and metabolism

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Preclinical studies suggest that GIPR antagonism helps with weight loss and metabolic improvements