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In addition to acting on neuronal cells, GLP-1R agonists also exert effects on microglia and astrocytes through cAMP/PKA signaling pathway

Han Y, Liu W, Chen L, Xin X, Wang Q, Zhang X, et al

Preclinical and clinical studies, in fact, demonstrate that glucagon receptor agonism in combination with GLP-1 receptor agonism reduces glucose levels and enables weight loss

10.1001/jama.2023.24945

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