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This effectiveness is due to tirzepatides dual mechanism, acting as both a glucose-dependent insulinotropic polypeptide (GIP) and a glucagon-like peptide-1 (GLP-1) receptor agonist

Preserving Muscle Mass While Losing Weight on GLP-1 Therapy Rapid weight loss without resistance training can result in 2535% of lost weight coming from lean muscle rather than fat

Tip: Keep a symptom diary noting meal composition, timing, and weekly weight change

During the first trimester, when organ systems are forming, any disruption to maternal nutrition or blood glucose stability could theoretically increase miscarriage risk or birth defects, though direct causation has not been proven in humans

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