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85 Transcriptional analyses of FRCs in TDLNs have provided evidence of microenvironmental reprogramming, including the expansion and structural reorganization of stromal compartments and the suppression of CCL21 and IL-7 production by FRCs, enabling greater tumor cell immune evasion and impaired immune cell homing

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GLP1/E significantly ameliorated also insulin sensitivity, as denoted by ITT and HOMA-IR, regardless of the dose, and reduced basal insulin levels (Fig